Problems associated with substance use are on the rise among women in northern Nigeria, creating a need to understand factors contributing to this trend. Data on substance use, symptoms of substance use disorder (SUD) using DSM-5 criteria, and risk and protective factors associated with SUD symptoms, including adverse childhood experiences (ACE), were collected in a community-based study of young adult women (M age = 25.76, SD = 4.71 years) from Katsina State.